Join a team of committed, enthusiastic scientists seeking a wholistic cure for cancer.


OPEN POSITIONS:

Interested applicants should send their CV and cover letter to [email protected]

SystImmune is an Equal Opportunity Employer


Director Immuno-Oncology

SystImmune is a newly-established, fast-growing antibody therapeutics company located in Redmond, Washington. We are seeking highly motivated immunologists with direct experiences in the area of immune-oncology. The successful candidates should have a broad expertise in many aspects of immunology and oncology including the immune response against cancer cells, T cell, NK cell, or myeloid suppressor cell biology, antibody drug development and target validation. The successful candidates must be highly-organized, detail-oriented, and be able to multitask in a fast-paced and dynamic startup environment.

The ideal candidates:

Have led projects in biotechnology or pharmaceutical industry setting in the discovery and development of monoclonal or bi-specific antibody therapeutics that activate the immune system to recognize and eliminate cancer cells.

Can demonstrate a deep knowledge and understanding of tumor microenvironment, T cell, dendritic cell, NK cell, and microphage biology/immunology, etc.

Have solid hands-on experiences in cell-based assay development and in vivo animal models study design for immune-oncology targets.

Expected to:

  • Establish and apply in vitro, in vivo, and ex vivo assays and models to identify and, characterize novel therapeutics in order , and to select lead candidates

  • Evaluate novel pathways and mechanisms for immunological therapeutic intervention and formulate strategies for bispecific and combination approaches.

  • Drive innovation through a deep understanding of the immunology fieldimmunology and the application of new technologies and methods

  • Manage direct reports

  • Develop and deliver scientific presentations and reports

  • Participate in the evaluation of licensing opportunities

  • Work as part of a highly collaborative interdisciplinary team in an integrated research laboratory

  • Build strong relationships with peers and cross functionally with partners outside of the team to enable higher performance

  • Learn fast and can change course quickly where indicated

  • Strive for rigorous scientific excellenc

  • Create a learning environment and be open to suggestions and experimentation for improvement

  • Embrace the ideas of others, nurtures innovation, and manages innovation to reality

Experience:

  • PhD; MS; BS in Immunology, Biology, Biochemistry or a related field with 8+ years (PhD); 14+ years (MS); 16+ years (BS) of relevant academic and/or pharmaceutical or biotech experience

  • Demonstrated expertise in the discovery and development of biologics as therapeutic interventions

  • Proficiency in a wide range of immunological laboratory techniques

    • Multi-color flow cytometry (4+ colors)

    • Identification/sorting/experimentation of T cell/dendritic cell/NK cell biology

    • Cytotoxic T cell killing

    • Dendritic cell activation and modulation of the immune response

    • NK cell killing

    • Apoptosis

    • Cell proliferation

    • Differentiation

    • Internalization

    • Cytokine profiling

  • Experience/expertise in various High Content Screening (HCS) and High Throughput Screening (HTS) platforms is a plus, but not required

  • Ability to communicate scientific concepts and strategies effectively in a science setting

  • Excellent verbal and written communication and interpersonal skills to work across functions and across sites, and within academic and biotech collaborations

  • Experience leading teams and managing scientists